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ACE2 Antibody - middle region

ACE2 Antibody - middle region

ArtNr	OASG00144
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies By Cell Type Immunohistochemistry Western Blot ELISA Cardiovascular Research Heart Failure Myocardial Infarction Primary Antibodies By Organ Immunostaining Uterine, Ovarian & Cervical Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons. Int J Mol Sci. 22, (2020). 33375653 Expression of ACE2 in Human Neurons Supports the Neuro-Invasive Potential of COVID-19 Virus. Cell Mol Neurobiol. NULL, NULL (2020). 32623546
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACEH
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Targets	N-glycosylation on Asn-90 may limit SARS infectivity. Proteolytic cleavage by ADAM17 generates a secreted form. Also cleaved by serine proteases: TMPRSS2, TMPRSS11D and HPN/TMPRSS1.
Shipping Temperature	Wet Ice
Molecular Weight	90 kDa
Manufacturer - Application Additional Information	WB: 1:500-1:2000 ELISA: 1:40, 000 Optimal dilutions should be determined by the end user.
Gene symbol	ACE2
Gene Fullname	angiotensin I converting enzyme 2
Product format	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and storage	Store at -20°C. Avoid repeated freeze/thaw cycles.
Description of target	Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. (Microbial infection) Acts as a receptor for SARS coronavirus/SARS-CoV and human coronavirus NL63/HCoV-NL63.
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from the Internal region of human ACE2.
Manufacturer - Specificity	ACE2 Polyclonal Antibody detects endogenous levels of ACE2 protein.
Concentration	1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OASG00144-datasheet.pdf

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 30.10.2025

Express-Lieferung: 2 Tage sparen

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