IGF1R Antibody

ArtNr	OASG03739
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Sarcoma Cell Biology Cell Culture Cytokines Flow Cytometry Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IGFR,CD221,IGFIR,JTK13
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	145 kDa
Manufacturer - Application Additional Information	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
Gene symbol	IGF1R
Gene Fullname	insulin-like growth factor 1 receptor
Product format	Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and storage	Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from human IGF-IR around the non-phosphorylation site of Y1346. Location: 1280-1360aa.
Manufacturer - Specificity	IGF-IR Polyclonal Antibody detects endogenous levels of IGF-IR protein.
Concentration	1 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025

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