RELA Antibody (Acetyl-Lys122)

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

Wet Ice

RELA

Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Acetyl-NF kappa B-p65 (K122) polyclonal antibody detects endogenous levels of NF kappa B-p65 protein only when acetylation at K122.