RPS6KB1 Antibody (Phospho-Thr421)

Polyclonal Antibody

Phospho-Thr421

70 kDa

RPS6KB1

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Phospho-p70 S6 kinase Alpha (T421) Polyclonal Antibody detects endogenous levels of p70 S6 kinase Alpha protein only when phosphorylated at T421.