S100A1 Antibody - N-terminal region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

10 kDa

S100A1

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

S-100 Alpha Polyclonal Antibody detects endogenous levels of S-100 Alpha protein.