TBX3 Antibody - middle region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

79 kDa

TBX2, TBX3

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

TBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein.