CDCP1 ELISA Kit (Human) (OKCD00846)

CUB domain-containing protein 1

64866

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.6 Publications < p>Manually curated information for which there is published experimental evidence.< /p> < p>< a href="/manual/evidences#ECO:0000269">Moreâa‚¬A< /a>< /p> Manual assertion based on experiment iniRef.1"Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer."_x005F_x000D_ Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N._x005F_x000D_ Oncogene 20:4402-4408(2001) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, VARIANT GLY-709.Ref.3"Adhesion signaling by a novel mitotic substrate of src kinases."_x005F_x000D_ Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M._x005F_x000D_ Oncogene 24:5333-5343(2005) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 30-34 AND 369-375, IDENTIFICATION BY MASS SPECTROMETRY, PHOSPHORYLATION, GLYCOSYLATION, TISSUE SPECIFICITY, INTERACTION WITH CDH2; CDH3; SDC1; SDC4 AND ST14, FUNCTION.Ref.9"Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein."_x005F_x000D_ Xia Y., Gil S.G., Carter W.G._x005F_x000D_ J. Cell Biol. 132:727-740(1996) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, PHOSPHORYLATION.Ref.10"CDCP1 is a novel marker for hematopoietic stem cells."_x005F_x000D_ Conze T., Lammers R., Kuci S., Scherl-Mostageer M., Schweifer N., Kanz L., Buehring H.-J._x005F_x000D_ Ann. N. Y. Acad. Sci. 996:222-226(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.11"CDCP1 identifies a broad spectrum of normal and malignant stem/progenitor cell subsets of hematopoietic and nonhematopoietic origin."_x005F_x000D_ Buehring H.-J., Kuci S., Conze T., Rathke G., Bartolovic K., Gruenebach F., Scherl-Mostageer M., Bruemmendorf T.H., Schweifer N., Lammers R._x005F_x000D_ Stem Cells 22:334-343(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY.Ref.13"Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS."_x005F_x000D_ Andre M., Le Caer J.-P., Greco C., Planchon S., El Nemer W., Boucheix C., Rubinstein E., Chamot-Rooke J., Le Naour F._x005F_x000D_ Proteomics 6:1437-1449(2006) [PubMed] [Europe PMC] [Abstract]Cited for: IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION.

< 0.124 ng/mL