FABP5 Chemi-Luminescent ELISA Kit (Human)

ELISA Kit

Wet Ice

fatty acid binding protein 5

Intracellular carrier for long-chain fatty acids and related active lipids, such as the endocannabinoid, that regulates the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (PubMed:22170058). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation (PubMed:8092987).

NP_001435

Assay Methodology: Quantitative Sandwich ELISA

Chemiluminescent

Sample - 1:2 - 1:4 - 1:8 - 1:16
Serum (n=5) - 79-99% - 97-104% - 82-104% - 83-101%
EDTA Plasma (n=5) - 80-102% - 87-103% - 92-99% - 92-101%
Heparin Plasma (n=5) - 80-90% - 80-95% - 91-102% - 84-96%

Matrix - Recovery range (%) - Average(%)
Serum (n=5) - 96-104 - 101
EDTA Plasma (n=5) - 93-101 - 98
Heparin Plasma (n=5) - 81-95 - 87

Serum, plasma, tissue homogenates, cell lysates, and other biological fluids