HERPES SIMPLEX VIRUS 1 Antigen (OOSA09747)

Liquid. PBS, 0.1%Triton X-100.

Herpes simplex virus 1 (HSV1) is a member of the Herpesviridae viral family. It is a neurotropic virus that causes watery blisters on the skin or mucous membranes of humans. It is contagious and can be spread by close contact with an infected person who is producing and shedding virus from the skin. The virus is mostly latent in nerve cells of the body, but can occasionally travel to the skin, start shedding and may or may not produce the characteristic blisters. HSV1 is normally associated with cold sores on the mouth or lips, but may also be found on the genitals. There is no known cure for HSV infection and an infected person remains a carrier for life, however treatment can reduce viral shedding.
This product is a cell lysate that is useful for a range of techniques, but contains soluble cytoplasmic proteins from the production cells.

HSV1 is propagated in mammalian cells using a protocol optimised for maximum particle yield. At the appropriate time, infected cells are washed in saline and disrupted to release virus particles by freeze thaw and sonication.
Virus particles released from cells are partially purified by low speed centrifugation to remove cell debris. The product is then inactivated by heating to 56^oC for 2 hours and by the addition of 0.01% Triton X-100. Inactivity is confirmed by double blind passage.

Wet Ice