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NR3C1 Peptide - N-terminal region (AAP45593)

NR3C1 Peptide - N-terminal region (AAP45593)

ArtNr	AAP45593
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding By Cell Type Carcinoma Peptides & Proteins Immunohistochemistry Western Blot Peptides
Typ	Peptides
Format	Lyophilized powder
Applikationen	WB, IHC
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GCCR, GCR, GR, GRL
Similar products	NR3C1
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Description	This is a synthetic peptide designed for use in combination with anti-NR3C1 antibody (Catalog #: ARP45593_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	NR3C1
Protein size	777
Molecular weight	86kDa
Product format	Lyophilized powder
Gene id	2908
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	KDM5A, NCOA2, TP53, ADA, AR, BAG1, CALM1, CALR, CEBPA, CEBPB, CHD9, COPS6, CREB1, CREBBP, DAP3, DCAF6, DDX54, ECD, ETS1, ETS2, FKBP4, FYN, GRIP1, HNRNPU, HSP90AA1, HSPA1A, IDE, IFNGR2, JUN, KDM5A, KPNA2, LCK, MAPK1, MAPK15, MAPK8, MDM2, MED14, NCL, NCOA1, NCOA2, NCOA6, NCOR1, NCOR2, NFKB1, NFKB2, NR2F2, NR2F6, NR3C1, NR3C2, NRIP1, ONECUT1, PBX1, POU1F1, POU2F1, POU2F2, PPARGC1A, PRKACA, PRKDC, PSMC3IP, PTGES3, PTMS, RAF1, RELA, RNF14, SFN, SLC25A4, SMAD3, SMARCA2, SMARCA4, SMARCB1, SMARCC1, SMARCD1, SMARCE1, STAT3, STAT5A, STAT5B, SUMO1, SUMO4, SYT1, TBP, TGFB1I1, TP53, TRIM24, TRIM28, TSG101, TXN, UBB, UBE2I, YWHAH, ZBTB16, ADA, ARPC5, BAG1, CALR, CEBPA, CEBPB, CREB1, CREBBP, DAP3, DAXX, DDX54, ECD, ETS2, FKBP4, HMGB1, HMGB2, HNRNPU, HOXB1, HSP90AA1, HSPA1A, HSPD1, JUN, KDM5A, MED1, MED14, NCL, NCOA1, NCOA2, NCOA3, NCOA4, NCOA6, NCOR1, NCOR2, NEDD4L, NFKB1, NFKB2, NR2F6, NR3C1, NR3C2, NRIP1, ONECUT1, PBX1, PIAS2, POU1F1, POU2F1, POU2F2, PPARGC1A, PSMC3IP, PTGES3, Psmc3ip, RAD9A, RAF1, RAN, RANBP9, RELA, SFN, SFPQ, SMAD3, SMARCA4, SMARCC1, SMARCD1, SMARCE1, STAT3, STAT5B, SVIL, TADA2A, TBP, TDG, TGFB1I1, TP53, TRIM24, TRIM28, TSG101, TXN, YWHAH, ZBTB16
Description of target	NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

AAP45593-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 100 ug

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Lieferung vsl. bis 30.10.2025

Express-Lieferung: 17 Tage sparen

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