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MRGPRX1 Peptide - C-terminal region (AAP59925)

MRGPRX1 Peptide - C-terminal region (AAP59925)

ArtNr	AAP59925
Hersteller	AVIVA Systems Biology
Menge	100ug
Kategorie	Food Safety Histamines Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Western Blot Peptides Other Lipid\Cholesterol Metabolism Modulators
Typ	Peptides
Format	Lyophilized powder
Applikationen	WB
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GPCR, MRGX1, SNSR4
Similar products	MRGPRX1
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Description	This is a synthetic peptide designed for use in combination with anti-MRGPRX1 Antibody (ARP59925_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	MRGPRX1
Protein size	322
Molecular weight	36kDa
Product format	Lyophilized powder
Gene id	259249
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	MRGPRX1 is an orphan receptor. MRGPRX1 is probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRX1 is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. MRGPRX1 is activated by the antimalarial drug, chloroquine and may mediate chloroquine-induced itch, in an histamine-independent manner.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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AAP59925-datasheet.pdf

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