CITED2 Peptide - middle region (AAP89613)

ArtNr	AAP89613
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Myeloma Sarcoma Peptides & Proteins Mesothelioma Cardiovascular Research Atherosclerosis Peptides By Organ Testicular & Prostate Cancer
Typ	Peptides
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mrg1,Msg2,p35srj,AI835299,ER154-like
Lieferbar
Manufacturer - Type	Blocking Peptide
Molecular Weight	23 kDa
Description	This is a synthetic peptide designed for use in combination with anti- CITED2 Antibody (ARP89613_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	CITED2
Protein size	214
Product format	Lyophilized powder
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
Nucleotide accession_num	NM_010828.3
Protein accession_num	NP_034958.2

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Arbeitsanleitung (Data Sheet) anfordern

AAP89613-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 100 ug

lieferbar

Lieferung vsl. bis 30.10.2025