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IL6R Peptide - C-terminal region (AAP97694)

ArtNr AAP97694
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL6Q,gp80,CD126,IL6RA,IL6RQ,IL-6RA,IL-6R-1
Lieferbar
Manufacturer - Type
Blocking Peptide
Molecular Weight
52 kDa
Description
This is a synthetic peptide designed for use in combination with anti- IL6R Antibody (ARP97694_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol
IL6R
Protein size
468
Product format
Lyophilized powder
Reconstitution and storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Nucleotide accession_num
NM_000565.3
Protein accession_num
NP_000556.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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