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Human CD95 (SOLUBLE) Protein (OPSA11040)

ArtNr OPSA11040
Hersteller AVIVA Systems Biology
Menge 25 ug
Kategorie
Typ Proteins Recombinant
Applikationen FA
Specific against Human (Homo sapiens)
Purity >95% by SDS PAGE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias APT1,CD95,FAS1,APO-1,FASTM,ALPS1A,TNFRSF6,FAS
Similar products FAS
Lieferbar
Manufacturer - Applications
Functional Assays: 20
- 100ug/ml
Description
RECOMBINANT HUMAN CD95 (SOLUBLE)
Gene symbol
FAS
Protein size
335
Reconstitution and storage
Store at -20C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Description of target
RECOMBINANT HUMAN CD95 (SOLUBLE)
Homology
Human
Manufacturer - Specificity
CD95, also known as Fas/APO-1, is a death-domain (DD) containing type I membrane glycoprotein and member of the TNF receptor superfamily, expressed by activated T and B cells, neutrophils, monocytes and thymocytes, which binds to its ligand CD95L (FasL/CD178) to mediate apoptosis. The soluble form of CD95 (sCD95), generated by alternative splicing of CD95 mRNA, has the ability to inhibit target cell apoptosis by neutralizing CD95L. Elevated levels of sCD95 have been detected in patients with systemic lupus erythematosus (SLE), and have been associated with a poor prognosis in renal cell cancer and melanoma patients. This product can be used in functional studies to inhibit sCD95/CD95L mediated lysis of CD95 sensitive cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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