BCL2 Recombinant Protein

Protein

Root Catalog/Products/Recombinant Proteins

28kDa

B cell leukemia/lymphoma 2

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).

NP_033871.2

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.