GREM1 Recombinant Protein

ArtNr	OPCD03676
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Oncology Neuroscience Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Hematology Myeloma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Immunoprecipitation Western Blot ELISA SDS-PAGE
Typ	Proteins Recombinant
Applikationen	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated; HIS
Purity	> 97%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	C15DUPq;cell proliferation-inducing gene 2 protein;CKTSF1B1;colorectal adenoma and carcinoma 1;CRAC1;CRCS4;cysteine knot superfamily 1,BMP antagonist 1;DAN domain family member 2;DAND2;down-regulated in Mos-transformed cells protein;DRM;DUP15q;GREMLIN;gremlin 1,cysteine knot superfamily,homolog;gremlin 1-like protein;gremlin-1;hereditary mixed polyposis syndrome;HMPS;HMPS1;IHG-2;Increased in high glucose protein 2;increased in high glucose-2;MPSH;PIG2.
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Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	23kDa
Gene symbol	GREM1
Gene Fullname	gremlin 1, DAN family BMP antagonist
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
Nucleotide accession_num	NM_001191323.1
Protein accession_num	NP_001178252.1
Protein name	Gremlin-1
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OPCD03676-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 30.10.2025

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