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ITGB2 Recombinant Protein

ITGB2 Recombinant Protein

ArtNr	OPCD04592
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Neural Signaling By Cell Type Carcinoma Hematology Leukemia Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunoprecipitation Western Blot ELISA SDS-PAGE Oligodendrocyte Markers
Typ	Proteins Recombinant
Applikationen	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated; MBP, HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD18;cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor);Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;complement component 3 receptor 3 and 4 subunit;complement receptor C3 beta-subunit;Complement receptor C3 subunit beta;integrin beta chain,beta 2;integrin beta-2;integrin,beta 2 (complement component 3 receptor 3 and 4 subunit);LAD;LCAMB;leukocyte cell adhesion molecule CD18;leukocyte-associated antigens CD18/11A,CD18/11B,CD18/11C;LFA-1;MAC-1;MF17;MFI7;truncated integrin beta-2.
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Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	Two N-terminal Tags, His-tag and MBP-tag
Molecular Weight	70kDa
Gene symbol	ITGB2
Gene Fullname	integrin subunit beta 2
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992, PubMed:28807980). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407).
Nucleotide accession_num	NM_000211.4
Protein accession_num	NP_000202.3
Protein name	Integrin beta-2
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OPCD04592-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 25.12.2025

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