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MASP1 Recombinant Protein

ArtNr OPCD05138
Hersteller AVIVA Systems Biology
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Applikationen WB, SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Unconjugated; HIS
Purity > 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 3MC1;C4/C2 activating component of Ra-reactive factor;complement factor MASP-3;complement-activating component of Ra-reactive factor;CRARF;CRARF1;mannan binding lectin serine peptidase 1;mannan-binding lectin serine protease 1;mannose-associated serine protease 1;mannose-binding lectin-associated serine protease 1;mannose-binding protein-associated serine protease;MAP1;MAP-1;MAp44;MASP;MASP3;MASP-3;PRSS5;Ra-reactive factor serine protease p100;RaRF;serine protease 5.
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Manufacturer - Type
Protein
Manufacturer - Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Manufacturer - Category
Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag
N-terminal His Tag
Molecular Weight
53kDa
Gene symbol
MASP1
Gene Fullname
MBL associated serine protease 1
Protein size
Recombinant
Product format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage
2°C to 8°C|-80°C
Description of target
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development (PubMed:21258343).
Nucleotide accession_num
NM_001031849.2
Protein accession_num
NP_001027019.1
Protein name
Mannan-binding lectin serine protease 1
Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration
200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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