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BMI1 Recombinant Protein

BMI1 Recombinant Protein

ArtNr	OPCD06009
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Carcinoma Hematology Leukemia Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Typ	Proteins Recombinant
Applikationen	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B lymphoma Mo-MLV insertion region 1 homolog;BMI1;BMI1 polycomb ring finger oncogene;BMI1 polycomb ring finger proto-oncogene;COMMD3-BMI1 read-through protein;flvi-2/bmi-1;FLVI2/BMI1;murine leukemia viral (bmi-1) oncogene homolog;PCGF4;polycomb complex protein BMI-1;polycomb group protein Bmi1;polycomb group RING finger protein 4;ring finger protein 51;RNF51.
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Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	24kDa
Gene symbol	BMI1\|COMMD3-BMI1
Gene Fullname	BMI1 proto-oncogene, polycomb ring finger\|COMMD3-BMI1 readthrough
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373). The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed:21772249, PubMed:25355358). In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:26151332, PubMed:21772249).
Nucleotide accession_num	NM_001204062.1
Protein accession_num	NP_001190991.1
Protein name	Polycomb complex protein BMI-1
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OPCD06009-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 30.10.2025