PIK3C3 Recombinant Protein

Protein

Root Catalog/Products/Recombinant Proteins

33kDa

phosphatidylinositol 3-kinase catalytic subunit type 3

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).

NP_002638.2

200 ug/mL (prior to lyoph)