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SMAD2 Recombinant Protein

SMAD2 Recombinant Protein

ArtNr	OPCD07063
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Adenocarcinoma Immunoprecipitation Western Blot ELISA SDS-PAGE By Organ Colorectal Cancer Neurodegeneration Markers
Typ	Proteins Recombinant
Applikationen	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	hMAD-2;hSMAD2;JV18;JV18-1;MAD homolog 2;MADH2;MADR2;Mad-related protein 2;mother against DPP homolog 2;mothers against decapentaplegic homolog 2;Sma- and Mad-related protein 2;SMAD family member 2;SMAD,mothers against DPP homolog 2.
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Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	26kDa
Gene symbol	SMAD2
Gene Fullname	SMAD family member 2
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Nucleotide accession_num	NM_001003652.3
Protein accession_num	NP_001003652.1
Protein name	Mothers against decapentaplegic homolog 2
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OPCD07063-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 25.12.2025

Express-Lieferung: 2 Tage sparen

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