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Tnf Recombinant Protein (Mouse)

Tnf Recombinant Protein (Mouse)

ArtNr	OPED00139
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Status Necrosis Apoptosis ELISA Immunostaining
Typ	Proteins Recombinant
Format	Lyophilized
Applikationen	ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Purity	>90% (SDS-PAGE)
Citations	A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils: B. Geering, et al.; Blood 117, 5953 (2011), Application(s): Death assay on mouse neutrophils, Abstract; Full Text Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4: K. Burns, et al.; J. Exp. Med. 197, 263 (2003), Abstract; Full Text Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity: P. Schneider, et al.; J. Exp. Med. 187, 1205 (1998), Abstract; Full Text General Literature References The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor: M. Grell, et al.; Cell 83, 793 (1995), Abstract; The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death: C.A. Smith, et al.; Cell 76, 959 (1994), Abstract; Tumor necrosis factor: a pleiotropic cytokine and therapeutic target: K.J. Tracey & A. Cerami; Annu. Rev. Med. 45, 491 (1994), Abstract;
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	cachectin;DI;DIF;Tn;TNF-;Tnfa;TNF-a;TNFalpha;TNF-alpha;Tnfs;Tnfsf1a;TNFSF2;Tnlg1f;tumor necrosis factor;tumor necrosis factor ligand 1f;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Wet Ice
Molecular Weight	20 kDa
Manufacturer - Application Additional Information	ELISA: binds to human TNF-R1 receptor.
Gene symbol	Tnf
Gene Fullname	tumor necrosis factor
Protein size	Recombinant
Product format	Lyophilized. Contains PBS.
Reconstitution and storage	Reconstitute with 50 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. Store at -20C
Description of target	Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Nucleotide accession_num	NC_002945.3
Protein accession_num	NP_854111.1
Protein name	Tumor necrosis factor

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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