BDNF Protein (OPPA00472)

Hersteller AVIVA Systems Biology
Kategorie
Typ Proteins
Specific against other
Format The protein was lyophilized without additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Menge 2ug
Host E.coli
ArtNr OPPA00472
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene symbol
BDNF
Protein name
Brain-derived neurotrophic factor
Molecular weight
27 kDa
Product format
Lyophilized without additives.
Physical appearance: Sterile filtered white powder..
Gene id
627
Reconstitution and storage
It is recommended to reconstitute the lyophilized Brain-derived Neurotrophic Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Lyophilized BDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Brain-derived Neurotrophic Factor should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target
BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. the versatility of bdnf is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Purification
BDNF Human Recombinant is purified by proprietary chromatographic techniques.
Biological activity
The ED50, calculated by the dose-dependent induction of ACHE (acetylcholine esterase) in rat basal forebrain primary septal culture is 50 ng/ml corresponding to a Specific Activity of 20, 000IU/mg.
Purity
Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

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Menge: 2ug
Lieferbar: In stock
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