Hersteller |
AVIVA Systems Biology
|
Kategorie |
|
Typ |
Proteins |
Specific against |
other |
Format |
Lyophilized from a concentrated (1mg/ml) solution in water containing 5mM Sodium Phosphate buffer, pH 7.4 + 80 mM NaCl. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
Menge |
5ug |
Host |
E.coli |
ArtNr |
OPPA00568 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Gene symbol |
KGF 2 |
Protein name |
Fibroblast growth factor 10 |
Protein size |
170 |
Molecular weight |
19.3 kDa |
Product format |
Lyophilized from 0.2um filtered concentrated solution in PBS, pH 7.4. Physical Appearance: Sterile filtered white lyophilized powder. |
Gene id |
2255 |
Reconstitution and storage |
Reconstitution: It is recommended to reconstitute the lyophilized FGF-10 in sterile 18M omega-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions. Storage: Lyophilized Keratinocyte Growth Factor-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution FGF10 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Description of target |
KGF-2 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. |
Purification |
Purified by proprietary chromatographic techniques. |
Biological activity |
The ED50, calculated by the dose-dependant stimulation of FGF receptors by BaF3 indicator cells (measured by 3H-thymidine uptake) is < 0.5 ng/ml, corresponding to a specific activity of 2x106 units/mg. |
Purity |
Greater than 96.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
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