KGF 2 Protein (OPPA00568)

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Hersteller AVIVA Systems Biology
Kategorie
Typ Proteins
Specific against other
Format Lyophilized from a concentrated (1mg/ml) solution in water containing 5mM Sodium Phosphate buffer, pH 7.4 + 80 mM NaCl. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Menge 5ug
Host E.coli
ArtNr OPPA00568
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene symbol
KGF 2
Protein name
Fibroblast growth factor 10
Protein size
170
Molecular weight
19.3 kDa
Product format
Lyophilized from 0.2um filtered concentrated solution in PBS, pH 7.4.
Physical Appearance: Sterile filtered white lyophilized powder.
Gene id
2255
Reconstitution and storage
Reconstitution: It is recommended to reconstitute the lyophilized FGF-10 in sterile 18M omega-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Storage: Lyophilized Keratinocyte Growth Factor-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution FGF10 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target
KGF-2 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
Purification
Purified by proprietary chromatographic techniques.
Biological activity
The ED50, calculated by the dose-dependant stimulation of FGF receptors by BaF3 indicator cells (measured by 3H-thymidine uptake) is < 0.5 ng/ml, corresponding to a specific activity of 2x106 units/mg.
Purity
Greater than 96.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

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Menge: 5ug
Lieferbar: In stock
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