Hersteller |
AVIVA Systems Biology
|
Kategorie |
|
Typ |
Proteins |
Specific against |
other |
Format |
The protein was lyophilized with 5mM NaP, pH-8.0 & 100mM NaCl. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
Menge |
2ug |
Host |
E.coli |
ArtNr |
OPPA00573 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Gene symbol |
M CSF |
Protein name |
Macrophage colony-stimulating factor 1 |
Molecular weight |
37 kDa |
Product format |
Lyophilized 5mM NaP (pH 8.0) and 100mM NaCl Physical Appearance: Sterile filtered white freeze-dried powder |
Gene id |
1435 |
Reconstitution and storage |
It is recommended to reconstitute the lyophilized M-CSF in sterile 18M Omega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Lyophilized Macrophage Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution MCSF should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles. |
Description of target |
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. MCSF induces cells of the monocyte/macrophage lineage. MCSF plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids. |
Biological activity |
The ED50, calculated by the dose-dependent stimulation of the proliferation of murine M-NFS-60 indicator cells was found to be <2.0 ng/mL, corresponding to a specific activity of 500, 000 Units/mg. |
Purity |
Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
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