Recombinant Human IL4 Protein

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Wet Ice

IL4

Liquid. 20mM Tris-HCl and 10% glycerol Physical Appearance: Sterile filtered clear solution

Interleukin-4 Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 150 amino acid fragments (25-153) and is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors. The IL-4 is fused to a 20 amino acid His-tag at N-terminus.

Interleukin-4

The ED₅₀ for this effect is <1.8 ng/mL. Measured in cell proliferation assay using TF1 human erythroleukemic cells.