TRIM21 Protein

Root Catalog/Products/Recombinant Proteins

Wet Ice

TRIM21

Liquid. 20mM HEPES pH 7.5, 0.01mM EDTA and 0.02% SDS.
Physical Appearance: Sterile filtered clear solution

TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.

E3 ubiquitin-protein ligase TRIM21

0.99 mg/ml