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Bax Protein (OPPA01324)

Bax Protein (OPPA01324)

Hersteller	AVIVA Systems Biology
Kategorie	Proteins
Typ	Proteins
Specific against	other
Format	The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. Physical appearance: Sterile Filtered colorless solution.
Menge	2ug
Host	E.coli
ArtNr	OPPA01324
eClass 6.1	34160400
eClass 9.0	42020190
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Gene symbol	mBAX
Protein name	Apoptosis regulator BAX
Product format	The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. Physical appearance: Sterile Filtered colorless solution.
Gene id	12028
Reconstitution and storage	Mouse Bax although stable at 12C for 1 week, should be stored desiccated below -18C. Please prevent freeze-thaw cycles.
Description of target	Bcl-2 - associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
Purification	The Mouse Bax is purified by proprietary chromatographic techniques.
Purity	Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Drywet	Wet Ice

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