Human sL-Selectin ELISA Kit

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human sL-Selectin. The Human sL-Selectin ELISA is for research use only. Not for diagnostic or therapeutic procedures. Human L-Selectin (leukocyte selectin, CD62L, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, DREG, lymph node homing receptor, MEL-14 antigen) is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. Two forms of Soluble L-Selectin (sL-Selectin) have been reported. sL-Selectin derived from lymphocytes is about 62 kDa, while the fragment derived from neutrophils is 75-100 kDa. sL-Selectin can inhibit the binding of lymphocytes to endothelium at high concentrations, suggesting a possible role in modulating this binding in vivo. Monitoring of sL-Selectin levels in serum provides more detailed insights in several pathological situations such as sepsis and acquired immune deficiency syndrome (AIDS).

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

9.46 pg/ml

90 % - 119 %

1066.0 - 1718.8 ng/ml

1.7 % - 7.3 %