Human MCP-1/CCL2 ELISA Kit

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human MCP-1/CCL2. The Human MCP-1/CCL2 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Monocyte Chemotactic Protein-1 (MCP-1, CCL2, MCAF, TDCF) is a small cytokine that belongs to the CC chemokine family. MCP-1 is a monomeric polypeptide, with a molecular weight of approximately 13 kDa. MCP-1 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. MCP-1 is primarily secreted by monocytes, macrophages and dendritic cells. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Monitoring of MCP-1 levels in serum provides more detailed insights in several pathological situations such as sepsis, Crohn’s disease, lupus nephritis, amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, acute pancreatitis, atherosclerosis, gastric carcinoma, esophageal squamous cell carcinoma, malignant glioma, and ovarian, pancreatic, bladder, and breast cancers.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

2.18 pg/ml

95 % - 118 %

40.2 - 589.9 pg/ml

5.3 % - 7.1 %