Mouse IL-6 High Sensitivity ELISA Kit

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-6. The Mouse IL-6 High Sensitivity ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Mature mouse IL-6 is 187 amino acids (aa) in length and shares 39% and 85% aa sequence identity with human and rat IL-6. IL-6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. IL-6 also plays a role in fighting infection, as IL-6 has been shown in mice to be required for resistance against bacteriumStreptococcus pneumoniae. IL-6 stimulates the inflammatory and auto-immune processes in many diseases such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, Behçet's disease, and rheumatoid arthritis. Advanced/ metastatic cancer patients have higher levels of IL-6 in their blood.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

0.43 pg/ml

82 % - 93 %

n.d. - 126.8 pg/ml

4.6% - 5.2 %