IL-17AF ELISA Kit, Mouse

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17AF. The Mouse IL-17AF ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. Of the six IL-17 family members, IL-17A and IL-17F share the strongest homology (50% amino acid identity) and the two genes are located in the same chromosomal region. IL-17A and IL-17F have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma. IL-17A expression is associated with many inflammatory diseases in humans, such as rheumatoid arthritis, multiple sclerosis, asthma, systemic lupus erythematosus, and allograft rejection. Expression of IL-17F is also linked with human inflammatory diseases, including asthma.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

4.54 pg/ml

73 % - 125 %

n.d. - 205.5 pg/ml

4.4 % - 7.7 %