Pax-8 Polyclonal Antibody

PAX8 encodes a member of the paired box (PAX) family of transcription factors. Members of PAX8 family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in PAX8 have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

1 mg/ml

48119

-20°C for one year