Anti-Human CD20 APC

ArtNr	02311-80-100
Hersteller	BioGems
Menge	100 tests
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Flow Cytometry Primary Antibodies By Organ Bladder Cancer Gastric Cancer
Typ	Antibody
Format	APC
Applikationen	FC
Clon	2H7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Konjugat/Tag	APC
Citations	Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Polyak, M. J., & Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes, heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood, 99(9), 3256-3262. Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

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