Anti-Human CD32 APC

ArtNr	04411-80-100
Hersteller	BioGems
Menge	100 tests
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies
Typ	Antibody
Format	APC
Applikationen	FC
Clon	6C4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	APC
Citations	VELY, F., GRUEL, N., MONCUIT, J., COCHET, O., ROUARD, H., DARE, S., ... & TEILLAUD, J. L. (1997). A new set of monoclonal antibodies against human FcγRII (CD32) and FcγRIII (CD16): characterization and use in various assays. Hybridoma, 16(6), 519-528. Liebert, M. A. (1997). 6C4, 2B2, 3D3. Hybridoma, 16(6). Bouhlal, H., Martinvalet, D., Teillaud, J. L., Fridman, C., Kazatchkine, M. D., Bayry, J., ... & Kaveri, S. V. (2014). Natural Autoantibodies to Fcγ Receptors in Intravenous Immunoglobulins. Journal of clinical immunology, 1-8.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDA polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells, and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Inflammation

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04411-80-100-safety-datasheet.pdf