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Anti-Human CD62L (L-Selectin) SAFIRE Purified

Anti-Human CD62L (L-Selectin) SAFIRE Purified

ArtNr	04731-25-500
Hersteller	BioGems
Menge	500 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Signaling Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Format	SAFIRE Purified
Applikationen	FC
Clon	DREG-56
Specific against	Human (Homo sapiens)
Host	Rat
Isotype	IgG2a Kappa
Citations	Gallatin, W. M., Weissman, I. L., & Butcher, E. C. (1982). A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature, 304(5921), 30-34. Siegelman, M. H., Cheng, I. C., Weissman, I. L., & Wakeland, E. K. (1990). The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding. Cell, 61(4), 611-622. Pizcueta, P., & Luscinskas, F. W. (1994). Monoclonal antibody blockade of L-selectin inhibits mononuclear leukocyte recruitment to inflammatory sites in vivo. The American journal of pathology, 145(2), 461.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity, Angiogenesis
Format	SAFIRE Purified

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04731-25-500-datasheet.pdf

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