Anti-Human CD14 PE

ArtNr	06211-60-25
Hersteller	BioGems
Menge	25 tests
Kategorie	Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody
Format	PE
Applikationen	FC
Clon	61D3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	PE
Citations	Nunez, G., Ugolini, V., Capra, J. D., & Stastny, P. (1982). Monoclonal Antibodies against Human Monocytes. Scandinavian journal of immunology,16(6), 515-523 Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature, 392(6675), 505-509. Henriksen, P. A., Devitt, A., Kotelevtsev, Y., & Sallenave, J. M. (2004). Gene delivery of the elastase inhibitor elafin protects macrophages from neutrophil elastase-mediated impairment of apoptotic cell recognition. FEBS letters,574(1), 80-84.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Innate Immunity

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

06211-60-25-datasheet.pdf

06211-60-25-safety-datasheet.pdf