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Anti-Human CD54 (ICAM-1) FITC

Anti-Human CD54 (ICAM-1) FITC

ArtNr	06611-50-25
Hersteller	BioGems
Menge	25 tests
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Format	FITC
Applikationen	WB, FC, IHC
Clon	15.2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	FITC
Citations	Bhattacharya, A. L. O. K., Dorf, M. E., & Springer, T. A. (1981). A shared alloantigenic determinant on Ia antigens encoded by the IA and IE subregions: evidence for I region gene duplication. The Journal of Immunology, 127(6), 2488-2495. Mendiratta, S. K., Singh, N., Bal, V., & Rath, S. (1996). Analysis of T-cell hybridomas with an unusual MHC class II-dependent ligand specificity.Immunology, 89(2), 238-244. Unternaehrer, J. J., Chow, A., Pypaert, M., Inaba, K., & Mellman, I. (2007). The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proceedings of the National Academy of Sciences,104(1), 234-239.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). ICAM-1 is also known CD 54 and is expressed on non-hematopoietic cells of vascular endothelial, thymic epithelial, fibroblasts lineages, and on hematopoietic cells like macrophages, mitogen-stimulated T-lymphoblasts, dendritic cells in tonsils, lymph nodes and Peyer’s patches, and germinal center B cells. Inflammatory mediators (IL-1, TNF, IFN-γ) enhance the production of ICAM-1 on fibroblasts and endothelial cells within few hours. Thus, ICAM-1 seems to be the marker of inflammatory reactions.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Angiogenesis

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06611-50-25-datasheet.pdf

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