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Anti-Human CD49d Purified 100 ug

Anti-Human CD49d Purified 100 ug

ArtNr	11511-20-100
Hersteller	BioGems
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Primary Antibodies
Typ	Antibody
Format	Purified
Applikationen	FC, IHC
Clon	9F10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rätzschke, O., & Falk, K. (2009). CD49d provides access to -œuntouched- human Foxp3+ Treg free of contaminating effector cells. Blood, 113(4), 827-836. Hemler, M. E. (1990). VLA proteins in the integrin family: structures, functions, and their role on leukocytes. Annual review of immunology, 8(1), 365-400.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 9F10 monoclonal antibody specifically reacts with human CD49d, the 150 kDA alpha 4 integrin chain. The molecule forms the heterodimer called VLA-4 with integrin beta 1 and another heterodimer with integrin beta 7 that binds fibronectin, VCAM-1, and MadCAM-1. CD49d is expressed on monocytes, lymphocytes, thymocytes, NK cells, B cells, and T cells. It is involved in hematopoietic stem cell differentiation, cell migration, and cell activation. Its absence on Foxp3+ cells make it a useful marker to isolate Treg cell populations.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Adaptive Immunity, Angiogenesis
Format	Purified

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11511-20-100-datasheet.pdf

11511-20-100-safety-datasheet.pdf