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Anti-Human CD116 FITC

Anti-Human CD116 FITC

ArtNr	18211-50-100
Hersteller	BioGems
Menge	100 tests
Kategorie	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody
Format	FITC
Applikationen	FC
Clon	4H1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	FITC
Citations	Woodcock, J. M., McClure, B. J., Stomski, F. C., Elliott, M. J., Bagley, C. J., & Lopez, A. F. (1997). The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5. Blood, 90(8), 3005-3017. Lopez, A. F., Vadas, M. A., Woodcock, J. M., Milton, S. E., Lewis, A., Elliott, M. J., ... & Park, L. S. (1991). Interleukin-5, interleukin-3, and granulocyte-macrophage colony-stimulating factor cross-compete for binding to cell surface receptors on human eosinophils. Journal of Biological Chemistry, 266(36), 24741-24747. Guthridge, M. A., Barry, E. F., Felquer, F. A., McClure, B. J., Stomski, F. C., Ramshaw, H., & Lopez, A. F. (2004). The phosphoserine-585-"dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kB and induction of bcl-2. Blood, 103(3), 820-827.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 4H1 monoclonal antibody specifically bind to human CD116, a 70-85 kD alpha chain of the GM-CSF receptor. It forms the high affinity GM-CSF receptor with CD131 as the beta chain. CD116 is expressed on macrophages, monocytes, eosinophils, dendritic cells, fibroblasts, neutrophils, and some tumor cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity, Angiogenesis

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18211-50-100-datasheet.pdf

18211-50-100-safety-datasheet.pdf