Anti-Human IL-17A PE

ArtNr	73811-60-100
Hersteller	BioGems
Menge	100 tests
Kategorie	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Typ	Antibody
Format	PE
Applikationen	FC
Clon	4H1524
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Konjugat/Tag	PE
Citations	McAllister, F., Henry, A., Kreindler, J. L., Dubin, P. J., Ulrich, L., Steele, C., ... & Kolls, J. K. (2005). Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-α and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. The Journal of Immunology, 175(1), 404-412. Iwakura, Y., Nakae, S., Saijo, S., & Ishigame, H. (2008). The roles of IL-17A in inflammatory immune responses and host defense against pathogens.Immunological reviews, 226(1), 57-79.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 4H1524 monoclonal antibody specifically binds to human IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

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73811-60-100-datasheet.pdf

73811-60-100-safety-datasheet.pdf