Vergleich

Anti-Human/Mouse CD62P (P-Selectin) PE

ArtNr 04721-60-25
Hersteller BioGems
Menge 25 ug
Kategorie
Typ Antibody
Format PE
Applikationen FC
Clon Psel.KO2.3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag PE
Citations Massaguer, A., Engel, P., Perez-del-Pulgar, S., Bosch, J., & Pizcueta, P. (2000). Production and characterization of monoclonal antibodies against conserved epitopes of P-selectin (CD62P). Tissue antigens, 56(2), 117-128.
Kansas, G. S. (1996). Selectins and their ligands: current concepts and controversies. Blood, 88(9), 3259-3287.
Bullard, D. C., Kunkel, E. J., Kubo, H., Hicks, M. J., Lorenzo, I., Doyle, N. A., ... & Beaudet, A. L. (1996). Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. The Journal of experimental medicine, 183(5), 2329-2336.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Description
The Psel.KO2.3 monoclonal antibody specifically reacts with mouse CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as granule membrane protein 140 (GMP-140). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils. The Psel.KO2.3 antibody does not block adhesion and binds to an epitope common to several species including mouse, human, and rat.
Storage Temperature
4C
Formulation
Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest
Adaptive Immunity, Angiogenesis

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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