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Anti-Mouse Ly-6G (Gr-1) SAFIRE Purified

Anti-Mouse Ly-6G (Gr-1) SAFIRE Purified

ArtNr	83122-25-1000
Hersteller	BioGems
Menge	1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies By Organ Bone Cancer
Typ	Antibody
Format	SAFIRE Purified
Applikationen	FC, IP, IHC
Clon	RB6-8C5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Citations	Fleming, T. J., Fleming, M. L., & Malek, T. R. (1993). Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.The Journal of Immunology, 151(5), 2399-2408. Hestdal, K., Ruscetti, F. W., Ihle, J. N., Jacobsen, S. E., Dubois, C. M., Kopp, W. C., ... & Keller, J. R. (1991). Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. The Journal of Immunology,147(1), 22-28. Huang, B., Zhao, J., Shen, S., Li, H., He, K. L., Shen, G. X., ... & Feng, Z. H. (2007). Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Research, 67(9), 4346-4352.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1). The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils. As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity
Format	SAFIRE Purified

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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83122-25-1000-datasheet.pdf

83122-25-1000-safety-datasheet.pdf