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Anti-Mouse IL-12/IL-23 p40 SAFIRE Purified

Anti-Mouse IL-12/IL-23 p40 SAFIRE Purified

ArtNr	83312-25-500
Hersteller	BioGems
Menge	500 ug
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody
Format	SAFIRE Purified
Applikationen	WB, FC, IF, IP, ELISA
Clon	C17.8
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Wysocka, M., Kubin, M., Vieira, L. Q., Ozmen, L., Garotta, G., Scott, P., & Trinchieri, G. (1995). Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. European journal of immunology, 25(3), 672-676. Cho, D., Lee, W. J., Halloran, P. J., Trinchieri, G., & Kim, Y. B. (1996). Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cellular immunology, 172(1), 29-34. D'Andrea, A., Rengaraju, M., Valiante, N. M., Chehimi, J., Kubin, M., Aste, M., ... & Nickbarg, E. (1992). Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. The Journal of experimental medicine, 176(5), 1387-1398.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Innate Immunity
Format	SAFIRE Purified

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83312-25-500-datasheet.pdf

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