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Anti-Mouse/Rat IL-17A FITC

Anti-Mouse/Rat IL-17A FITC

ArtNr	73812-50-25
Hersteller	BioGems
Menge	25 ug
Kategorie	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody
Format	FITC
Applikationen	FC
Clon	17B7
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG2a Kappa
Konjugat/Tag	FITC
Citations	Wu, S., Rhee, K. J., Albesiano, E., Rabizadeh, S., Wu, X., Yen, H. R., ... & Sears, C. L. (2009). A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nature medicine, 15(9), 1016-1022. Cao, H., Lan, Q., Shi, Q., Zhou, X., Liu, G., Liu, J., ... & Liu, Z. (2011). Anti-IL-23 antibody blockade of IL-23/IL-17 pathway attenuates airway obliteration in rat orthotopic tracheal transplantation. International immunopharmacology, 11(5), 569-575. Yan, S., Wang, L., Liu, N., Wang, Y., & Chu, Y. (2012). Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis.Immunology and cell biology, 90(4), 421-428.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity, Cytokines & Growth Factors

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

73812-50-25-datasheet.pdf

73812-50-25-safety-datasheet.pdf