Antibodies

TPMT Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human
Menge 50ug
Host Rabbit
ArtNr BM-CAC08328-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Isotype info
Recombinant human Thiopurine S-methyltransferase protein (4-244AA)
Immunogen
ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Conjugation
Unconjugated
Alternative Names
Thiopurine methyltransferase
UniProt ID
P51580
Purification
>95%, Protein G purified
Storage
-20°C
Expiry Date
1 year
Shipping Condition
Ice packs
Comments
Conjugation service and the corresponding secondary antibody are available.
Technical Notes
TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 50ug
Lieferbar: In stock
Listenpreis: 217,22 €
Rabatt: -10,0%
Preis: 195,50 €
Sie sparen: 21,72 €
lieferbar

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