Hersteller |
Biomatik
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
Equine |
Menge |
100ug |
ArtNr |
BM-RPC26544-100ug |
Targets |
IL1B |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Gene Name |
IL1B |
Alternative Names |
Interleukin-1 beta Short name: IL-1 beta |
Uniprot |
Q28386 |
Source |
E.coli |
Expression Region |
116-268aa |
AA Sequence |
AAMHSVNCRL RDIYHKSLVL SGACELQAVH LN GENTNQQV VFCMSFVQGE EETDKIPVAL GLKE KNLYLS CGMKDGKPTL QLETVDPNTY PKRKME KRFV FNKMEIKGNV EFESAMYPNW YISTSQAE KS PVFLGNTRGG RDITDFIMEI TSA |
Sequence Info |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Theoretical MW |
17.3 kDa |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Storage Buffer |
Lyophilized from a 0.2 um filtered PBS, pH 7.4, 0.1 % Tween-80 |
Endotoxin Level |
Less than 1.0 EU/ug as determined by LAL method. |
Biological Activity |
The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 20 pg/ml, corresponding to a specific activity of ? 5.0 x 107 IU/mg. |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
Function |
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
Subcellular location |
Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted |
Protein Families |
IL-1 family |
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