Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

hnRNP M (HNRPM) (NAGR1)

E.coli

AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGP KGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRY RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP LKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGM ITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANL DYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGI GTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER ALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPID ANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEG PFGGGMENMGRFGSGMNMGRINEILSNALKRGEII AKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGA GLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIER MGPLGLDHMASSIERMGQTMERIGSGVERMGAGMG FGLERMAAPIDRVGQTIERMGSGVERMGPAIERMG LSMERMVPAGMGAGLERMGPVMDRMATGLERMGAN NLERMGLERMGANSLERMGLERMGANSLERMGPAM GPALGAGIERMGLAMGGGGGASFDRAIEMERGNFG GSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTW KMLKDKFNECGHVLYADIKMENGKSKGCGVVKFES PEVAERACRMMNGMKLSGREIDVRIDRNA

N-terminal 6xHis-tagged

>85% as determined by SDS-PAGE.

Not tested

Ice packs

1 year

Pre-mRNA binding protein in vivo, binds avidly to poly and poly RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.