« Zurück
Startseite /
Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A) (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A) (Active)

ArtNr	BM-RPC26714-1mg
Hersteller	Biomatik
Menge	1 mg
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis By Organ Lymphatic System Cancer
Typ	Proteins Recombinant
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265
Similar products	Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265
Lieferbar
Gene Name	TNFRSF11A, RANK
Alternative Names	Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265
Uniprot	Q9Y6Q6
Source	E.coli
Expression Region	29-202aa
AA Sequence	QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KC TTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVC DTGKAL VAVVAGNSTT PRRCACTAGY HWSQDC ECCR RNTECAPGLG AQHPLQLNKD TVCKPCLA GY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK
Sequence Info	Partial
Tag Info	Tag-Free
Theoretical MW	19.1 kDa
Purity	>98% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered 20 mM Tris-HCl, pH 8.0, 150mM NaCl
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of ? 2.0 x 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269\|PubMed:9878548}.
Function	Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.
Involvement in disease	Familial expansile osteolysis (FEO); Paget disease of bone 2, early-onset (PDB2); Osteopetrosis, autosomal recessive 7 (OPTB7)
Subcellular location	Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform RANK-e5a: Cell membrane, Single-pass type I membrane protein
Tissue Specificity	Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Paythway	NF-kappaBsignalingpathway

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 1 mg

lieferbar

Lieferung vsl. bis 12.02.2026

Express-Lieferung: 1 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern