Recombinant Human Carbonic anhydrase 7 (CA7) (Active)

Carbonic Anhydrase 7, Carbonate Dehydratase VII, Carbonic Anhydrase VII, CA-VII, CA7

E.coli

MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINI ISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQV DFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV GSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAP DGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTK AQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVT WIVLREPICISERQMGKFRSLLFTSEDDERIHMVN NFRPPQPLKGRVVKASFRA

C-terminal 6xHis-tagged

>95% as determined by SDS-PAGE.

Less than 1.0 EU/ug as determined by LAL method.

Ice packs

1 year

Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore, Alpha-carbonic anhydrase is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA7 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine, but it is inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.

Cytoplasm